Long Lost Nitght Timing Tablet in Pindi Bhattian - 03067788111

Islamabad, Islamabad, PK 2000.00 Rs.

1 month ago New Sell 1 hit ID #49761


Long Lost Night Sildenafil & Dapoxetine 60mg Erectile Dysfunction in Premature Ejaculation
Long Lost Night Tablet in Pakistan Part of the physiological process of erection involves the parasympathetic nervous system causing the release of nitric oxide (NO) in the Corpus cavernosum of the penis. No binds to the receptors of the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), Leading To Smooth Muscle Relaxation (vasodilation) in the corpuscavernosum, resulting in increased inflow of blood and an erection.

Long lost Night Tablet Sildenafil 142mg
Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for the degradation of cGMP in the corpus cavernosum. the molecular structure of Sildenafil id similar to that of cGMP and acts as a competitive binding agent of PDE5 I=in the corpus cavernosum, resulting in more cGMP and better erections.

Dapoxetine 60mg Tablet
Dapoxetine exhibits its efficacy by primarily inhibiting the reuptake of the serotonin transporter. It was also shown to bind and inhibit the reuptake transporters of dopamine & norepinephrine.

Pharmacokinetics Sildenafil:
The onset of action: 60 minutes
duration: 2-4 hours
Absorption: rapid, slower with a high-fat meal
Distribution: Vdss: 105 L
Protein binding, plasma: 96% Metabolism: Hepatic via CYP3A4 (MAJOR AND cyp2c9 ( minor route)
Bioavailability: 40%
Half-life elimination: 4 Hours
Time To Peak: 30-120 minutes; delayed by 60 minutes with a high-fat meal.

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